![]() In the current circumstances of evolution of resistance, especially to the glycopeptides, with the appearance of glycopeptide-resistant Enterococcus, and metronidazole-resistant C. difficile has not been systematically determined. ![]() Other therapeutic agents have been used in combination, such as rifampin. ![]() The most frequently used therapeutic substances are glycopeptides (vancomycin, teicoplanin) and imidazoles (metronidazole). The treatment of these infections consists of stopping preliminary antibiotherapy and the introduction of specific antibiotherapy directed against C. difficile of endogenous or exogenous origin. ![]() These pathologies occur most often after antibiotic treatment inducing a disruption of the intestinal barrier and allowing the emergence of C. Clostridium difficile is responsible for a syndrome ranging from mild or moderate diarrhea to severe pseudomembranous colitis. ![]()
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